Toxicology Project Leader job opportunity at Roche.

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DatePosted 29 Days Ago bot
Roche Toxicology Project Leader
Experience: 1-years
Pattern: full-time
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loacation Shanghai, China
loacation Shanghai....China

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position Toxicology Project Leader The position is within the toxicology group in Pharmaceutical Sciences (PS) and located at China Innovation Center of Roche (CICoR). This group leads in the development of the non-clinical safety assessment of drug candidates during the discovery and development phases at Roche. Your responsibilities are: ·         Developing and executing high quality, timely, integrated and scientifically sound nonclinical safety strategies from target assessment through discovery and global clinical development. ·         Representing the toxicology function on multi-functional project teams and acting as a key contributor to the selection and development of potential new medicines through close interactions with other functions such as DMPK, biology, CMC and clinical development. ·         Generating concise safety assessments and leading efforts of investigating mechanisms of toxicity for internal decision making, accountable for result analysis and interpretation, trouble shooting, as well as contributing to protocol/report of safety studies and related documentation. ·         Developing and optimizing immunosafety and immunogenicity assay strategies to characterize candidate molecules ·         Managing assay outsourcing to local and global CROs and develop/troubleshoot mechanistic immunosafety and immunogenicity assays in house where needed ·         Collaborating with global subject matter experts (SMEs) and external partners to provide relevant immunosafety and immunogenicity input locally where needed and act as local SME In addition, you are expected to: ·         Live the culture of humility, curiosity, and responsibility ·         Embrace agile ways of working and collaborative spirit ·         Aim for scientific excellence, embrace innovation and utilize emerging technologies to support risk assessments with continuous learning ·         Expand scientific visibility and maintain effective interactions with internal and external collaborators, and contribute to scientific advancements in the toxicology and immunosafety/immunogenicity field Profile: You have a Doctor of Veterinary Medicine (DVM), PhD (immunology/toxicology or pharmacology preferred) or equivalent and >1 year of post-doc/working experience in relevant immunology/toxicology areas. Large molecule toxicology and immunosafety/immunogenicity experience is preferred. Good knowledge of toxicology including common safety assessment strategy and technology. Strong interpersonal skills and team player. Good organizational and multi-tasking abilities. Good English communication and presentation skills.     Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

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