Senior Scientist - Pathology & Immunology job opportunity at WashU.

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WashU Senior Scientist - Pathology & Immunology
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Pattern: full-time
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loacation Washington University Medical Campus, United States Of America
loacation Washington Uni..........United States Of America

Scheduled Hours 40 Position Summary The main goal of our research is to better understand the link between the immune and the central nervous systems. We are particularly focused on how CD8 T cells are activated in the central nervous system, and how we can translate this knowledge into potential therapeutic strategies for neurodegeneration. Our latest work uncovered an unexpected role of CD8 T cells in a juvenile and slowly progressive form of the neurodegenerative disease Amyotrophic Lateral Sclerosis 4 (ALS4), which is caused by a mutation in the gene SETX. We found that clonally expanded CD8 T cells of likely autoimmune origin are progressively activated in the central nervous system (CNS) and blood of patients and mice. In ALS4 mice, clonal expansion of CD8 T cells in the CNS correlates with disease progression. Starting from these original results, our lab will further explore the role of CD8 T cells in the pathogenesis of several forms of ALS, in both humans and mice. Techniques include, but are not limited to, molecular biology and cloning, T cell transduction, flow cytometry, imaging, in vitro and in vivo assays, behavioral tests, and RNA-sequencing. Collaborates on designing, conducting and reporting of research projects. Job Description Primary Duties & Responsibilities: Collaborates on designing, conducting and reporting of research projects. Assists with grant preparation and reporting. Prepares and submits papers on research. Develops hypotheses to be tested and ways of testing it. Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions. Manages research project with other institutions and investigators. Performs other duties as assigned such as managing mouse colonies and laboratory operations Working Conditions: Works in a laboratory environment with potential exposure to biological, chemical and radioactive hazards. Must be physically able to wear protective equipment and to provide standard care to research animals. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time. Required Qualifications Education: Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education. Certifications /Professional Licenses : No specific certification/professional license is required for this position. Work Experience: Postdoctoral (3 Years) Skills: Not Applicable Driver's License: A driver's license is not required for this position. More About This Job WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles. Preferred Qualifications Education: No additional education unless stated elsewhere in the job posting. Certifications /Professional Licenses : No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: No additional work experience unless stated elsewhere in the job posting. Skills: Analytical Problem Solving, Laboratory Instrumentation, Laboratory Processes, Laboratory Techniques, Oral Communications, Teamwork, Working Independently, Written Communication Grade R12 Salary Range $63,400.00 - $115,000.00 / Annually The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget. Questions For frequently asked questions about the application process, please refer to our External Applicant FAQ . Accommodation If you are unable to use our online application system and would like an accommodation, please email   CandidateQuestions@wustl.edu   or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship. Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. Benefits Statement Personal Up to 22 days of vacation, 10 recognized holidays, and sick time. Competitive health insurance packages with priority appointments and lower copays/coinsurance. Take advantage of our free Metro transit U-Pass for eligible employees. WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%. Wellness Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more! Family We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered. WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us. For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/ EEO Statement Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

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